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CurSplash® Brain Boost

CurSplash® Brain Boost

CurSplash® Brain Boost is “Superfood” for your Supercomputer”.  Dr. formulated and clinically tested, this formula is not only powerful for feeding the brain it feeds the entire body!  After decades of research and scientific investigation, this World Class combination of 100% natural ingredients is arguably the best brain supplement on the market today.  The principal structure and functional nutrients in CurSplash® Brain Boost are a polysaccharide, multi-nutrient complex complemented by CurcuminPro®  BCD, TerraPro®, BiAloe®, and Annatto Tocotrienol.  Every ingredient has been carefully selected based on its individual scientific value and its collective contribution to the efficacy of the product.  The results speak for themselves. 

Note: Energy boost from this product may affect sleep if taken late in the evening.  For maximum benefit, allow 8 hours between doses.

$59.97 or $53.97 / month

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CurSplash® Brain Boost

SKU CPRO-CSP-BRB Categories ,

Additional information

Weight .5 oz
Dimensions 4.5 × 3.5 × 3.5 in

1 Bottle (60 Capsules)

Key Benefits

Clinical studies in humans have shown improvements in: 

  • Cognitive function (according to the ADAS-Cog cognition score, which is the gold standard for assessing cognition)
  • Immune function (according to the CD4/CD8 ratio, which is an overall indicator of how effective the immune system is working)
  • Inflammation (according to TNF-α and VEGF, which are used to assess the body’s response to stress or infection in an inflammatory state)
  • Adult stem cells (according to CD14+ cells, which are a marker of how well the body continues to produce stem cells).

Although not statistically significant, the research also showed that CurSplash Brain Boost caused brain derived neurotrophic factor to modestly increase, which is well known for its critical roles in the brain regions that are involved in neurosynaptic function, apoptosis, plasticity, long-term potentiation, learning memory processes, and higher-order thinking. Thus, compared to other vitamins for the brain, CurSplash Brain Boost has superior efficacy, and it does not contain any caffeine, which is a known stimulant that temporarily creates a sense of focus and well-being, only to subside after its effect wanes.

In addition to CurSplash Brain Boost’s effect on brain health, such as being sharper, more focused, having better memory, and quicker recall, other key benefits have been reported as well. For example, some people report more energy and a better overall sense of well-being, you may notice a quicker recovery from being sick or stressed out, you may start to have longer, deeper, and more refreshing sleep, and you may have a generally happier and more balanced mood. In addition, other people find that they have improved stomach and bowel function, and still other people notice that they have better skin, hair, and nails. Thus, while CurSplash Brain Boost is targeted for people searching for brain health supplements, you can anticipate the possibility of feeling its benefits in other areas, too.

Quality Ingredients

CurSplash Brain Boost is the best supplement for your brain that is backed by many years of research and is designed to give you significant nutritional support, not only for brain health but for every cell in your body.  Each ingredient is included for specific reasons to support your health.  Here are some important details about the ingredients in the formula. 

CurSplash® Brain Boost Benefits:


Note: CurSplash® Brain Boost does NOT contain potentially harmful Black Pepper Extracts


Why are Polysaccharides Important?

The field of glycobiology (the study of the biology, biosynthesis, and structure of carbohydrates, saccharides, or sugars) shows us that the process of glycosylation (i.e., the reaction in which a polysaccharide (carbohydrate or sugar) is attached to a protein or fat to form what is called a glycoconjugate) is a very important function in our cells. These glycoconjugates are bioactive compounds that help to guide the way many of our cells function. The cells use these glycoconjugates for many different purposes, including to help regulate our immune system’s function and activity and for cells to communicate with one another. If we do not provide our cells with the needed amounts of polysaccharides in the diet to execute these basic functions, then we are not living optimally. 

The body is smart enough to take other, common simple sugars, like glucose and fructose, which are typically eaten too often, and transform them into the required polysaccharides needed for glycosylation, but this appears to be an inefficient way to enable our cells to function properly. 

Taking CurSplash Brain Boost every day is the best way to ensure that you are getting the right types and amounts of polysaccharides that are so important to not only glycosylation, but supporting all of the body’s functions, and ultimately to allow you to feel healthy.



Atherosclerosis, Hypolipidemia, Myocardial Infraction


Eczema, Scabies, Scleroderma, Psoriasis, Wounds


Bronchitis, Cystic Fibrosis, Asthma, Cough and Cold


Arthritis, Osteoprosis,



Brain & Nervous System

Alzheimer’s, Parkinson’s, Multiple Sclerosis, Epilepsy, Depression


Breast, Prostate, Colon, Brain, Skin, Bladder, Stomach, and more

Gastrointestinal & Liver

IBD, Ulcerative Colitis, Gastric Ulcer, Pancreatitis, and Hepatitis

Polysaccharides (sugars with a complex biochemical structure) constitute a class of nutrients that are important for health.  Most importantly, during the second major step of biosynthesis in all cells, nine molecules of mannose, a key polysaccharide found in BiAloe® in CurSplash Brain Boost, are required in the endoplasmic reticulum to initiate the assembly of glycoproteins and glycolipids.  This process demonstrates that polysaccharides are used for glycosylation (i.e., the addition of saccharides to amino acid chains or free fatty acid chains) in the endoplasmic reticulum and the Golgi.  The significance of the coding capacity of polysaccharides in glycoproteins and glycolipids is documented in a series of review articles in Acta Anatomica (Denker, 1998).  The addition of nine molecules of mannose in three chains in the endoplasmic reticulum constitutes the establishment of a domain on which instructions for life processes are transmitted between cells.  In the Golgi, other polysaccharides are added, and the number of mannose units is modified to provide a code of information for conducting host defense, repair, growth, healing, and homeostasis.  This domain is the principal site for coordinating activities for the trillions of cells that make up the human body.

This fundamental supporting biochemistry is why supplying polysaccharides from food sources results in a broad spectrum of health-supporting benefits.  Additionally, concentrated levels of polysaccharides in dietary supplements, like CurSplash Brain Boost, compared to their levels in foods, take advantage of how a concentrated amount of nutrients allows a greater number of bioactive compounds to be created.

As mentioned above, BiAloe® is a very potent aloe polysaccharide, called acemannan or mannose, that has been shown to support the natural biochemical mechanisms of antiviral cells (Kahlon et al., 1991).  In humans, acemannan also supports cell processes that are:  antibacterial, anti-neoplastic, wound healing, intracellular stabilizing, rebalancing and adaptative for stressed cells, and able to increase the synthesis of reduced-glutathione, the principal intracellular antioxidant and multi-systems balancing compound (Dykman & Dykman, 1998; Everson et al., 1992; Kalebic et al., 1991; Lefkowitz et al., 2000; McDaniel, 1987, 1990; McDaniel et al., 2006).  Aloe vera extracts also have fractions with unique molecular and pharmacological profiles, e.g., one fraction displayed hematopoietic activity, while another fraction displayed anti-inflammatory activity, i.e., down-regulation of iNOS and TNF (Kim et al., 1999).

Thus, the documented cellular and physiological effects of the acemannan found in BiAloe® and other polysaccharides in CurSplash Brain Boost are very potent and can help to support brain health, but overall health as well.  If you already have a health challenge, then the use of these polysaccharides is even more important to counteract the complications and symptoms.  The positive effects of these polysaccharides are likely even more potent with an increasing daily dose.  To be sure, supplementing with polysaccharides from different sources provides the opportunity for you to receive a wide range of phytochemicals with multiple health benefits. For more information about the research on polysaccharides, go here.


Fogleman RW, Chapdelaine JM, Carpenter RH, McAnalley BH. Toxicologic Evaluation Injectable Acemannan in the Mouse, Rat and Dog.  Veterinary & Human Toxicology 992;34(2):144-147. PMID: 1609484.

Tizard IR, Carpenter RH, McAnalley BH, Kemp MC.  The biological activities of mannans and related complex carbohydrates.  Molecular Biotherapy, 1989;1(6):290-296.  PMID: 2692629

Kahlon JB, Kemp MC, Yawei N, Carpenter RH, Shannon WM, McAnalley BH.In Vitro Evaluation of the Synergistic Antiviral Effects of Acemannan in Combination with Azidothymidine and Acyclovir, Molecular Biotherapy, 1991;3(December):214-223.PMID: 1768365

Denker, H. (1998). Editor’s note. Acta Anatomica, 161, 5.

Dykman, K.D., & Dykman, R.A. (1998). Effect of nutritional supplements on attentional-deficit hyperactivity disorder. Integr Physiol Behav Sci, 33, 49-60.

Everson, G., Daggy, B., McKinley, C., & Story, J. (1992). Effects of psyllium hydrophilic mucilloid on LDL-cholesterol and bile acid synthesis in hypercholesterolemic men. J Lipid Res, 33, 1183-92.

Kahlon, J., Kemp, M., Carpenter, R., McAnalley, B., McDaniel, H.R., & Shannon, W. (1991). Inhibition of AIDS virus replication by acemannan in vitro. Molecular Biotherapy, 3(3), 127-135.

Kalebic, T., Kinter, A., Poli, G., Anderson, M., Meister, A., & Fauci, A. (1991). Suppression of human immunodeficiency virus expression in chronically infected monocytic cells by glutathione, glutathione ester, and N-acetylcysteine. Proc Natl Acad Sci U S A, 88(3), 986-990.

Kim, H., Kacew, S., & Lee, B. (1999). In vitro chemopreventive effects of plant polysaccharides (Aloe barbadensis miller, Lentinus edodes, Ganoderma lucidum and Coriolus versicolor). Carcinogenesis, 20, 1637-1640.

Lefkowitz, D., Stuart, R. Gnade, B., Roberts, E., & Lefkowitz, S. (2000). Effects of a glyconutrient on macrophage functions. Int J Immunopharmacol 22, 299-308.

McDaniel, H.R. (1987). Identification of a gigantic circulating monocytic cell in warm blooded animals. Paper presented at the Annual Meeting of the American Society of Clinical Pathology New Orleans, LA.

McDaniel, H.R. (1990). HIV-1 patients respond favorably to oral acemannan. Paper presented at the 6th International Conference on AIDS San Francisco, CA.

McDaniel, H.R., Smith, P., McDaniel, C., & Crenshaw, R. (2006). A multi-site pilot survey of micronutrients in Alzheimer’s patients. Paper presented at the 2nd Annual Glycomics Medical Conference: Science of Glycobiology Houston, TX.

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